Thomas P. S. Schricker, MD, PhD
Axe de recherche primaire:
Endocrinologie, diabète, nutrition et maladies rénales
Courriel:
Courriel Le but de la recherche:
Nos objectifs de recherche sont notamment : l’étude des mécanismes intervenant dans la perte protéique corporelle postopératoire en vue d’évaluer les stratégies d’anesthésie, de nutrition et de pharmacologie permettant d’atténuer la réaction catabolique lors d’une intervention de chirurgie abdominale majeure; l’étude du métabolisme du glucose et de l’insulinothérapie chez les patients qui subissent une intervention de chirurgie cardiaque.Catabolisme en chirurgie, anesthésie loco-régionale, métabolisme du glucose et des protéines, nutrition périopératoire
Mots-clés:
Catabolisme en chirurgie, anesthésie loco-régionale, métabolisme du glucose et des protéines, nutrition périopératoire
Emplacement:
Royal Victoria Hospital Publications:
Sato T, Carvalho G, Sato H, Lattermann R, Matsukawa T, Schricker T: Glucose and insulin administration while maintaining normoglycemia during cardiac surgery using a computer assisted algorithm. Diabetes Technol Ther 13: 79-84; 2011
Carvalho G, Pelletier P, Albacker T, Lachapelle K, Joannis D, Hatzakorzian R, Lattermann R, Sato H, Marette A, Schricker T: Cardioprotective effects of glucose and insulin administration while maintainingnormoglycemia (GIN therapy) in patients undergoing coronary artery bypass grafting. J Clin Endocrinol Metab 96: 1469-147; 2011
Sato H, Carvalho G, Sato T, Lattermann R, Matsukawa T, Schricker T: The association of preoperative glycemic control, intraoperative insulin sensitivity and outcomes after cardiac surgery. J Clin Endocrinol Metab 95: 4338-4344; 2010
Sato H, Lattermann R, Carvalho G, Sato T, Metrakos P, Hassanain M, Matsukawa T, Schricker T: Perioperative glucose and insulin administration while maintaining normoglycemia (GIN therapy) in patients undergoing major liver resection. Anesth Analg 110: 1711-1718; 2010
Albacker TB, Carvalho G, Schricker T, Lachapelle K: High-dose insulin therapy attenuates systemic inflammatory response in coronary artery bypass grafting patients. Ann Thor Surg 86: 20-28; 2008
Schricker T, Meterissian S, Lattermann R, Adegoke O, Marliss EB, Mazza L, Eberhart L, Carli F, Nitschman E, Wykes L: Anticatabolic effects of avoiding preoperative fasting by intravenous hypocaloric nutrition: a randomized clinical trial. Ann Surg 248: 1051-1059; 2008
POISE Study Group: Effects of extended-release metoprolol succinate in patients undergoing non-cardiac surgery (POISE trial): a randomized controlled trial. Lancet 371: 1839-1847; 2008
Schricker T, Gougeon R, Eberhart L, Wykes L, Mazza L, Carvalho G, Carli F: Type 2 diabetes mellitus and the catabolic response to surgery. Anesthesiology 102: 320-326; 2005
Schricker T, Meterissian S, Eberhardt L, Wykes L, Lattermann R, Carli F: Postoperative protein sparing with epidural analgesia and hypocaloric dextrose. Ann Surg 240: 916-921; 2004
Schricker T, Wykes L, Eberhart L, Lattermann R, Mazza L, Carli F: The anabolic effect of epidural blockade requires energy and substrate supply. Anesthesiology; 97: 943-951; 2002
